Development of the bladder.docVIP

Development of the bladder The bladder develops from the upper part of the urogenital sinus UGS and is connected with the allantois.The allantois is obliterated during the development and forms a fibrous cord, the urachus, which following birth becomes the median umbilical ligament.While the cloaca is being divided, the caudal, originally common part of the mesonephric duct Wolffian duct and the ureter anlage is taken up into the upper, postero-lateral wall of the urogenital sinus future bladder . The rapid growth of the back wall of the urogenital sinus has the result that the common lowest part of the ureter and the mesonephric duct Wolffian duct are both taken up into the bladder wall. Further complicated growth processes have the result that the ureteral orifices and the orifice locations of the mesonephric duct Wolffian duct go through a cranio-caudal position exchange during the course of the further development. The ureteral openings appear to migrate thereby in a cranio-lateral direction and the mesonephros orifices appear to be shifted caudo-medially. The triangular zone that is thus created is termed the vesical trigonum. In males, the wolffian duct forms the future deferent duct on both sides. Fig. 24 - Development of the bladder ?Legend 12345AB Primary urogenital sinusMesonephric duct Wolffian duct Ureter anlageCommon drainage urinarypassagesPelvic limb of the urogenital sinusPart of the genital tractPart of the urinary tract Fig. 24Dorsal view of the entry level of the mesonephric canal common extremities of the mesonephric duct Wolffian duct and the ureter while it is incorporated into the dorsal wall of the bladder. Animation Reversal of the orifice locations of the ureter and mesonephric duct Wolffian duct in the bladder wall The trigonum thus originates from the mesoderm while the ventral bladder wall has an endodermal origin. Later, though, the trigonum will be completely covered by endodermal epithelial ce