Evidence for impaired cellular cholesterol removal mediated by APO A-I containing lipoproteins in patients with familial lecithin cholesterol acyltransferase deficiency》.pdfVIP

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Evidence for impaired cellular cholesterol removal mediated by APO A-I containing lipoproteins in patients with familial lecithin cholesterol acyltransferase deficiency》.pdf

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Evidence for impaired cellular cholesterol removal mediated by APO A-I containing lipoproteins in patients with familial lecithin cholesterol acyltransferase deficiency》.pdf

BiochirnicaL et Biophysics ta ELSEVIER Biochimica et Biophysics Acta 1213 (1994) 295-301 Evidence for impaired cellular cholesterol removal mediated by apo A-I containing lipoproteins in patients with familial lecithin: cholesterol acyltransferase deficiency Takao Ohta a,*, Rie Nakamura a, Yoichiro Ikeda a, Jiri Frohlich b, Kouki Takata ‘, Yasushi Saito d, Seikoh ~oriuchi e, Ichiro ~atsuda a aDepartment ofPediatrics, Kumamoto University School of Medicine, l-1-1, Homo, Kumamoto-City, Kumamoto 860, Japan ’ Department of Pathology, University of British Columbia, Vancouver V6T 124, Canada ’ Hiroshima Railway Hospital, Hiroshima, Japan d Department of Chemical Laboratory and Medicine, Yamagata University School of Medicine, Japan ’ Second Department of Biocbem~t~, Kumamoto University School of Medicine, Kumamoto 860, Japan (Received 20 January 1994;accepted 29 March 1994) Abstract We investigated the cholesterol reducing capacity of two species of lipoproteins containing apo A-I, one containing only apo A-I (LpA-I) and the other containing apo A-I and apo A-II (LpA-I