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genefilter October 5, 2010 Anova A filter function for Analysis of Variance Description Anova returns a function of one argument with bindings for cov and p. The function, when evaluated, performs an ANOVA using cov as the covariate. It returns TRUE if the p value for a difference in means is less than p. Usage Anova(cov, p=0.05, na.rm=TRUE) Arguments cov The covariate. It must have length equal to the number of columns of the array that Anova will be applied to. p The p-value for the test. na.rm If set to TRUE any NA’s will be removed. Details The function returned by Anova uses lm to fit a linear model of the form lm(x ~ cov), where x is the set of gene expressions. The F statistic for an overall effect is computed and if it has a p -value less than p the function returns TRUE, otherwise it returns FALSE for that gene. Value Anova returns a function with bindings for cov and p that will perform a one-way ANOVA. The covariate can be continuous, in which case the test is for a linear effect for the covariate. Author(s) R. Gentleman See Also kOverA, lm 1 2 allNA Examples set.seed(123) af - Anova(c(rep(1,5),rep(2,5)), .01) af(rnorm(10)) allNA A filter function to determine if all elements of a vector are NA. Description allNA evaluates to FALSE if all elements of its argument are NA. anyNA evaluates to FALSE if any of the elements of its argument are NA. Usage allNA(x) anyNA(x) Arguments x The vector to test. Value FALSE if all elements o