重组人胰岛素样生长因子1工程菌的高密度发酵.pdfVIP

中国组织工程研究与临床康复第，3眷笫3嬲2009—01—15出版 JournalofCfinicalRehabilitativeTissue Research Medicine EngineeringJanuary15,2009V01．13,No．3 尼零Basic fermentationrecombinanthuman Highcell--density of ● 。nsulin．1ikehfactor一1 usniorg ineeribacteria★ eng ng Chen Jian—fen，Chen Wei—qing，Zhang Hong，HuWen—lang ———■■●●■■■—■——-—_—————————_—————■●—————-—_●●—-—●——一i——■_———■_——_—■●—■●—●■——————■●●—————■■■●—————_——————●——■———■■■——一 Ab吼ract of CoIIege Biological BACKGRoUND：Insulin．1ike an celIfactorwhich a rolein disease growthfactor-1(IGF-1)isimpodant playsspecialmany Environmental treatmentssuchasdiabetes．Theresearch to of bacteriafermentation is IGF·1 engineering productiontechnologygreat Engineering。 Industria¨zatiOnandtoclinicaI application． Shuren Zhejiang OBJECTIVE：Tothe lennentationand conditionofrecombinanthumaninsulin·like