Nucleocytoplasmic Distribution of Human RNA-editing Enzyme ADAR1 Is Modulated by Double-stranded RNA-binding Domains, a Leucine-rich Export Signal, and a Putative Dimerization Domain.PDFVIP

Molecular Biology of the Cell Vol. 13, 3822–3835, November 2002 Nucleocytoplasmic Distribution of Human RNA- editing Enzyme ADAR1 Is Modulated by Double- stranded RNA-binding Domains, a Leucine-rich Export Signal, and a Putative Dimerization Domain Alexander Strehblow, Martina Hallegger, and Michael F. Jantsch* Department of Cell Biology and Genetics, Institute of Botany, University of Vienna, A-1030 Vienna, Austria Submitted March 21, 2002; Revised June 18, 2002; Accepted July 29, 2001 Monitoring Editor: Joseph Gall The human RNA-editing enzyme adenosine deaminase that act