ace抑制剂在心血管病的应用.pptVIP

ACE抑制剂：囊括全部 六项强适应证 * * * * * * * * * * * * * * * * * Of the original 267 centers that participated in HOPE, 174 agreed to participate in extended follow-up (HOPE-TOO), representing 4528 patients.1 All patients were given open-label ACE inhibitor (the overwhelming majority received ramipril 10 mg). After a mean follow-up of 7.1 years in HOPE/HOPE-TOO, there was a 30% relative risk reduction in new-onset diabetes (relative risk 0.70; 95% CI, 0.57–0.86). Over the 2.6-year period of HOPE-TOO, there was a 34% relative risk reduction in new-onset diabetes (relative risk, 0.66; 95% CI, 0.46–0.96), s