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92 The Open Tropical Medicine Journal, 2008, 1, 92-100
Open Access
Implementing Intermittent Preventive Treatment for Malaria in
Pregnancy: Review of Prospects, Achievements, Challenges and
Agenda for Research
1,2,* 3 4 5
Godfrey Martin Mubyazi , Pascal Magnussen , Catherine Goodman , Ib Christian Bygbjerg ,
Andrew Yona Kitua1 3 3 6
, Øystein Evjen Olsen , Jens Byskov , Kristian Schultz Hansen and
Paul Bloch3
1National Institute for Medical Research, P.O Box 9653 Dar es Salaam, Tanzania; 2Amani Medical Research Centre,
P.O Box 81 Muheza, Tanzania; 3DBL - Centre for Health Research and Development, Faculty of Life Sciences, Univer-
sity of Copenhagen, Denmark; 4London School of Hygiene and Tropical Medicine, London, UK; 5Institute of Interna-
tional Health, Immunology and Microbiology, Faculty of Life Sciences, University of Copenhagen, Denmark and
6Department of Health Services Research, Institute of Public Health, University of Aarhus, Aarhus, Denmark
Abstract: Introduction : Implementing Intermittent Preventive Treatment for malaria in Pregnancy (IPTp) with sulfadox-
ine-pyrimethamine (SP) through antenatal care (ANC) clinics is recommended for malaria endemic countries. Vast bio-
medical literature on malaria prevention focuses more on the epidemiological and cost-effectiveness analyses of the ran-
domised controlled trials carried out in selected geographical settings. Such studies fail to elucidate
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