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Thyroid Neoplasms after Therapeutic strongRadiationstrong for Malignancies.pdf

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2397 Thyroid Neoplasms after Therapeutic Radiation for Malignancies during Childhood or Adolescence Suchitra Acharya, M.D.1 BACKGROUND. Recent data indicate that the risk of developing a thyroid neoplasm 1 Kyriakie Sarafoglou, M.D. clearly is increased after high-dose, therapeutic radiation therapy during child- 2 Michael LaQuaglia, M.D. hood. To better understand the time course, natural history, and histopathology of 3 Skyler Lindsley, M.D. thyroid lesions that develop after high-dose irradiation, the authors undertook a 4 William Gerald, M.D. retrospective study of all survivors of childhood and adolescent malignancies who 5 Norma Wollner, M.D. were treated at Memorial Sloan-Kettering Cancer Center and who developed a 5 Charlotte Tan, M.D. clinically apparent thyroid neoplasm. Charles Sklar, M.D.5 METHODS. The authors searched the data base of the Department of Pediatrics, the hospital-based tumor registry, and the hospital medical records database for 1 Department of Pediatrics, New York Presbyterian patients with thyroid neoplasms. Hospital and Cornell-Weil Medical School, New RESULTS. Thirty-three patients were identiﬁed who developed a thyroid neoplasm York, New York.