abdomino pelvic irradiation after second-look laparotomy for stage iii ovarian carcinoma：腹盆腔照射卵巢癌iii期后第二看剖腹探查术.pdf

European Journal of Obstetrics Gynecology E L S E V I E R and ReproductiveBiology62 (1995)43-48 Abdomino pelvic irradiation after second-look laparotomy for stage III ovarian carcinoma S o p h i e C h a p e t *a, C h r i s t i n e B e r g e r a, A l a i n F i g n o n b, Gilles Calais a, F r a n c k F e t i s s o f ¢, A g n e s R e y n a u d - B o u g n o u x a, P h i l i p p e D e s c a m p s c, Gilles B o d y c, J a c q u e s L a n s a c c, Olivier le F l o c h a aClinique dOncologie et Radiothirapie, Centre Hospitalier et Universitaire, 2 Bd Tonnell~, 37044 Tours, France bDdpartement de Gyndcologie et Obstdtrique, Centre Hospitalier et Universitaire, 2 Bd Tonnelli, 37044 Tours, France CLaboratoire ddnatomo - - Pathologie, Centre Hospitalier et Universitaire, 2 Bd Tonnelld, 37044 Tours, France Received26 December 1994;revisionreceived 6 February 1995;accepted 3 April 1995 Abstract Objective: The purpose of this retrospective analysis of 34 patients with stage III ovarian carcinoma was to review results and morbidity of whole abdominal irradiation after surgery and chemotherapy. Methods and materials: All of the 34 patients had reach- ed a complete clinical remission after first cytoreductive surgery and chemotherapy. After second-look laparotomy each patient underwent whole abdominal irradiation. Except for two patients with chronic myelosuppression, the dose administered was of 22.5 Gy to the abdominal cavity with a boost of 22.5 Gy added to the pelvis. Results: Three and 5-year overall survival rates were 62% and 43%, r