nephrotic syndrome and interstitial nephritis associated with celecoxib：肾病综合征和间质性肾炎与昔布昔布.pdfVIP

CASE REPORTS Nephrotic Syndrome and Interstitial Nephritis Associated With Celecoxib Arnold B. Alper, Jr, MD, MPH, Suzanne Meleg-Smith, MD, and N. Kevin Krane, MD, FACP ● Nonsteroidal anti-inflammatory drugs (NSAIDs) are well known to cause fluid and electrolyte abnormalities and renal failure. NSAIDs also may cause an acute allergic interstitial nephritis (AIN) and the nephrotic syndrome characterized by histologic pathology consistent with minimal change disease in patients with previously normal renal