neurobiology of temporomandibular joint pain therapeutic implications：颞下颌关节疼痛的治疗影响神经生物学.pdfVIP

Neurobiology of Temporomandibular Joint Pain: Therapeutic Implications Ernest A. Jennings, Michael C. Williams, Vasiliki Staikopoulos, and Jason J. Ivanusic Persistent pain is the main reason for patient presentation with temporo- mandibular joint (TMJ) disorders. The pain is thought to result, at least in part, from sensitization of trigeminal sensory neurons that innervate the TMJ region. Sensitized sensory neurons can be hyperexcitable, responding both more readily and more vigorously to peripheral