Cardiac Motion Recovery Continuous Dynamics, Discrete.pptVIP

Integrative System Approaches to Medical Imaging and Image ComputingPhysiological Modeling In Situ ObservationRobust Integration Motivations Observing in situ living systems across temporal and spatial scales, analyzing and understanding the related structural and functional segregation and integration mechanisms through model-based strategies and data fusion, recognizing and classifying pathological extents and degrees Biomedical imaging Biomedical image computing and intervention Biological and physiological modeling Perspectives Recent biological technological breakthroughs, such as genomics and medical imaging, have made it possible to make objective and quantitative observations across temporal and spatial scales on population and on individuals At the population level, such rich information facilitates the development of a hierarchy of computational models dealing with (normal and pathological) biophysics at various scales but all linked so that parameters in one model are the inputs/outputs of models at a different spatial or temporal scale At the individual level, the challenge is to integrate complementary observation data, together with the computational modeling tailored to the anatomy, physiology and genetics of that individual, for diagnosis or treatment of that individual Perspectives In order to quantitatively understand specific human pathologies in terms of the altered model structures and/or parameters from normal physiology, the data-driven information recovery tasks must be properly addressed within the content of physiological plausibility and computational feasibility (for such inverse problems) Philosophy Integrative system approaches to biomedical imaging and image computing: System modeling of the biological/physiological phenomena and/or imaging processes: physical appropriateness, computational feasibility, and model uncertainties Observations on the phenomena: imaging and other medical data, typically corrupted by noises