沈阳地区人群tf7l2基因rs7903146-tc多态性与2型糖尿病的相关性.pdfVIP

·中文论著摘要· 型糖尿病的相关性 实验目的 性。 实验方法 采用聚合酶链反应．限制性片段长度多态性技术(PCR-RFLP)，对203例正常 个体和202例2型糖尿病患者TCF7L2基因塔7903146多态位点进行检测。 实验结果 璐7903146的等位基因T在对照组与病例组的频率分别为2．96％和7．18％，两 者之间有显著性差异。 结论 有相关性。 关键词 TCF7L2基因；2型糖尿病；基因多态性 ·英文论著摘要· rs7903146--T／C of between polymorphism Relationship in Geneand 2Diabetes TCF7L2 Type Shenyang Population ective Obj thers7903146-T／C ofTCF7L2 To the between polymorphism studyrelationship 2diabetesinHan of and shenyang． geneType population Methods 146．T／C wasdetectedin203 Hartcontrolsand The璐7903 polymorphism healthy 202 with 2diabetes PCR·I讧LPmethod． patientsType byusing Results were Theallele Tofrs7903146incontrol andthecase frequency groups betweenthetwo 5．91％and Wasstatisticaldifference groups· 14．36％respectively．There Conclusion with 2 ofTCF7L2 associated TherS7903146．T／C maybe Type polymorphism in Han diabetes Shenyangpopulation．