PYR_PYL_RCAR蛋白介导植物ABA的信号转导.pdfVIP

HEREDITAS (Beijing) 2012 5 , 34(5): 560―572 ISSN 0253-9772 综 述 DOI: 10.3724/SP.J.1005.2012.00560 PYR/PYL/RCAR 蛋白介导植物ABA 的信号转导 1,2 1,2 1,2 1,2 1,2 胡帅 , 王芳展 , 刘振宁 , 刘亚培 , 余小林 1. , 310058; 2. , 310058 脱落酸(ABA)在各个植物生长发育阶段以及植物对生物与非生物胁迫的响应过程中都发挥着重要的作 用。最近研究表明, 在ABA信号转导途径中有 3 种核心组份：ABA受体PYR/PYL/RCAR蛋白、负调控因子2C类蛋 白磷酸酶(PP2C) 和正调控因子SNF1 相关的蛋白激酶 2(SnRK2), 它们共同组成了一个双重负调控系统—— PYR/PYL/RCAR—| PP2C—| SnRK2 来调控ABA信号转导及其下游反应, 且3 种核心组份在植物体内的结合方 式受时空和生化等因素的影响, 通过特定组合形成的ABA信号转导复合体介导特定的ABA信号反应。文章就 PYR/PYL/RCAR 蛋白介导的植物ABA信号识别与转导途径的分子基础及其调控机制, 以及PYR/PYL/RCAR — PP2C —SnRK2 参与的ABA信号调控网络等研究进展做一概述, 并对该领域今后的研究进行了展望。 ABA; 信号转导; PYR/PYL/RCAR蛋白; PP2C; SnRK2 ABA signaling mediated by PYR/PYL/RCAR in plants HU Shuai1,2, WANG Fang-Zhan1,2, LIU Zhen-Ning1,2,, LIU Ya-Pei 1,2, YU Xiao-Lin1,2 1. Institute of Vegetable Sciences , Zhejiang University, Hangzhou 310058, China; 2. Key Laboratory of Horticultural Plant Growth , Development and Quality Improvement, Ministry of Agriculture , Hangzhou 310058, China Abstract: Abscisic acid (ABA) is a phytohormone that plays critical roles in numerous developmental stages as well as in adaptive responses to biotic and abiotic stresses. Recent breakthroughs in the field of ABA signaling have indicated that there are three major components, PYR/PYL/RCAR (an ABA receptor), type 2C protein phosphates (PP2C, a negative regulator), and SNF1-related protein kinase 2 (SnRK2, a positive regulator). Further results show that these three proteins construct a double negative regulatory system, PYR/PYL/RCAR—| PP2C—| SnRK2, to regulate ABA signal responses in pl