同时注射乙肝高效免疫球蛋白和卡介苗对.docVIP

同时注射乙肝高效免疫球蛋白和卡介苗对 　　【摘要】 目的：探讨同时注射乙肝高效免疫球蛋白（HBIG）和卡介苗对新生儿接种卡介苗效果的影响。方法：选取连州市妇幼保健院HbsAg（+）孕产妇及其新生儿作为观察组（100例），同期选取HbsAg（-）孕产妇及其新生儿作为对照组（96例），观察组新生儿出生后12 h内同时注射HBIG，接种乙肝疫苗与卡介苗，对照组新生儿新生儿出生后12 h接种乙肝疫苗与卡介苗，比较两组新生儿乙肝感染率、乙肝母婴传播有效阻断率、首次接种卡介苗成功率、红肿浸润时间、脓肿形成时间、结疤时间及卡疤大小。结果：两组新生儿乙肝感染率及乙肝母婴传播有效阻断率比较差异无统计学意义（P0.05）；观察组首次接种卡介苗成功率、卡疤黄豆大比例明显高于对照组，新生儿红肿浸润形成率、脓肿形成率明显低于对照组，红肿浸润时间与脓肿形成时间明显长于对照组，结疤时间明显短于对照组，比较差异均有统计学意义（P中国论文网 /6/view-7254785.htm 　　【关键词】 乙肝免疫球蛋白； 新生儿； 卡介苗接种 　　Influence Study on the Effect of Hepatitis B Immunoglobulin Combined with BCG Injection in the BCG Vaccination of Neonatal/SHI Hai-yan，CHENG Hai-bin，SHI Hai-xia.//Medical Innovation of China，2016，13（08）：138-141 　　【Abstract】 Objective：To investigate the effect of hepatitis B immunoglobulin combined with BCG injection in the BCG vaccination of newborns.Method：HbsAg（+） pregnant women and their newborns from the Maternal and Child Health Hospital of Lianzhou City were selected as the observation group（100 cases），HbsAg（-） pregnant women and their newborns were selected as the control group（96 cases）.The observation group was given HBIG injection，hepatitis B vaccination and BCG vaccine 12 hours after birth，the control group was given hepatitis B vaccination and BCG vaccine 12 hours after birth.The neonatal hepatitis B infection rate，HBV intrauterine transmission effectively blocking rate，success rate of the first BCG vaccination，swelling infiltration time，abscess formation time，scar time and size of card scar were compared between the two groups.Result：The differences in the neonatal hepatitis B infection rate and HBV intrauterine transmission effectively blocking rate of the two groups were not statistically significant（P0.05）.The success rate of the first BCG vaccination and the proportion of card scar big as soybeans in the observation group were significantly higher than those in the control group，the swelling infiltration rate and abscess formation rate of the observation group were significantly lower than those