应用远程近红外光诱导神经保护.docVIP

应用远程近红外光诱导的神经保护 目前针对神经退行性疾病的治疗策略及疗法大多只能对抑制症状和体征产生作用，而在减缓或阻止疾病进展方面作用较少。因此，迫切需要一种能够解决该疾病进展的治疗方法。在神经退行性疾病发病原因还难以明确的条件下，一些研究小组的证据表明，许多细胞和身体组织已经进化出自我保护和自我修复的系统，这可以作为非药物和无毒活化细胞的干预措施靶标；而且这些系统可以减轻甚至逆转退行性疾病的病程。其中许多干预措施已经开始试用了，光生物调节，组织在低能近红外光（NIR; 600-1,100nm）的照射下能够显示特别的治疗效果。 澳大利亚悉尼大学Daniel M. Johnstone教授研究小组在发表于《中国神经再生研究（英文版）》杂志3月第3期的观点文章中表示，最初进行试验的是光生物调节可作为促进剂用于病变皮肤和口腔粘膜的愈合，光生物调节现已证明可以在视网膜变性、创伤性脑损伤、急性缺血性脑卒中等啮齿动物模型以及阿尔茨海默病和帕金森病中显示出一定的治疗效果，能够减轻病理和功能缺陷。小样本但效果良好的临床对照试验已经实现了远程近红外光在减轻和减缓年龄相关黄斑变性和缓解轻度脑卒中方向的较好功效。 Article: Targeting the body to protect the brain: inducing neuroprotection with remotely-applied near infrared light by Daniel M. Johnstone1, 2 John Mitrofanis1, 3, Jonathan Stone1, 2 (1Bosch Institute, University of Sydney, New South Wales, Australia; 2 Discipline of Physiology, University of Sydney, New South Wales, Australia; 3 Discipline of Anatomy Histology, University of Sydney, New South Wales, Australia) Johnstone DM, Mitrofanis J, Stone J (2015) Targeting the body to protect the brain: inducing neuroprotection with remotely-applied near infrared light. Neural Regen Res 10(3):349-351. 欲获更多资讯：请与《》联络；联络电话：，或用电子邮件联络：eic@。/ Targeting the body to protect the brain: inducing neuroprotection with remotely-applied near infrared light Degeneration of the brain – in dementia, parkinsonism, motor neurone disease, macular degeneration – is still a feared but difficult to manage burden of ageing. Remarkable new ways of preventing, delaying, slowing these degenerations are emerging from understanding the ability of tissues to self-repair. One long-studied stimulus for this self-repair is photobiomodulation (PBM; treatment with red-infrared light). This study shows that PBM, even when directed at part of the body, induces tissue protection body-wide. The future of therapy for neurodegeneration may lie with these stress – inducible pan-body systems of protection. When the authors were students –when any of us were students –there were the organs of the body. The liver was in the