基因检测指导个体化用药.pptVIP

Human Genome Project in 2003 Finishing the euchromatic sequence of the human genome. Nature 2004; 431 (7011): 931-945. Phase I HapMap project in 2005 A haplotype map of the human genome. Nature 2005: 437(7063):1299-1320 Encyclopedia of DNA Elements project in 2007 Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007; 447(7146):799-816 1000 Genomes Project in 2008 DNA sequences. A plan to capture human diversity in 1000 genomes. Science 2008; 319(5863):395 从基因组出发，研究药物与基因组结构之间的关系，指导临床用药，达到个体化治疗目标。 个体化用药 以FDA批准药物说明书中遗