腔梗-20120918.pptVIP

有卒中事件的脑梗死 无症状性 腔隙性脑梗死 小血管病 腔隙 白质疏松 脑梗死 小血管病 组织病理 （急性缺血--坏死）--脑梗死 无症状性 腔隙性脑梗死 小血管病 脑梗死 白质疏松 腔隙 有卒中事件的脑梗死 大动脉 粥样硬化性 脑梗死 症状性 腔隙性脑梗死 穿支动脉疾病 动脉病理和机制 （内皮和调节功能及血脑屏障损害） 动脉病理和机制 （狭窄和/或内皮损害致血栓形成） 脑梗死 小血管病 （影像学改变） 这样是否更合理？ 脑梗死 小血管病 腔隙 白质疏松 小血管病 “草根天堂” “草根英雄” 欢迎大家到这里来，相信一定不会失望的 * Fisher CM. Lacunes: Small, deep cerebral infarcts. Neurology 1965;15:774–84. Arboix A, Martí-Vilalta JL. Lacunar stroke. Expert Rev Neurother. 2009 Feb;9(2):179-96. Review. Fisher CM. Lacunes: Small, deep cerebral infarcts. Neurology 1965;15:774–84. * Fisher CM. Lacunar strokes and infarcts: a review. Neurology. 1982;32:871-876 * Gan R, Sacco RL, Kargman DE, Roberts JK, Boden-Albala B, Gu Q. Testing the validity of the lacunar hypothesis: the Northern Manhattan Stroke Study experience. Neurology 1997; 48:1204–11. * See 1 citation found by title matching your search: Stroke. 2005 Dec;36(12):2583-8. Epub 2005 Nov 3. Lesion patterns and stroke mechanism in atherosclerotic middle cerebral artery disease: early diffusion-weighted imaging study. Lee DK, Kim JS, Kwon SU, Yoo SH, Kang DW. Source Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea. Abstract BACKGROUND AND PURPOSE: Patterns and mechanisms of stroke in patients with atherosclerotic middle cerebral artery (MCA) disease remain unclear. We sought to identify lesion patterns and stroke mechanisms associated with MCA disease using early diffusion-weighted imaging (DWI). METHODS: We reviewed 185 acute ischemic stroke patients who had (1) symptomatic lesions located in the unilateral MCA territory on DWI performed within 48 hours of symptom onset, and (2) either corresponding MCA disease, internal carotid artery disease, or cardioembolism. Acute DWI lesion patterns were classified as (1) single (small perforator 2 cm; large perforator or =2 cm; pial; large territorial; border-zone) and (2) multiple. RESULTS: MCA disease was diagnosed in 63 patients, 32 (50.8%) of whom showed multiple les