生物膜(高级生化课件).ppt

* * * 细菌外膜孔蛋白 periplasm * Hydrophific chennel largely hydrophobic exterier water filled * * * View down pore ，potassium channel Carbonyl sequence selectivity filter located diameter pore potassium * * Properties alkali cation desolvation re solvation sodium radius hydration * Rest open inactivated ball pore chain * Hydrated solute diffusion transporter * Binding transport dissociation recovery * Plasma membrane vesicle endocytosis exocytosis stimulation insulin * glucose * * * * * * Peptidoglycan integral peripheral cytosol maltose * Lactose fuel proton galactoside * Apical basal epithelial symporter uniporter facilitatea downhill efflux * pyruvate * * helix * Porin peptidoglycan plasma membrane outer membrane * Ankyrin spectrin junctional complex actin,chloride bicarbonate exchange * peripheral * Anchored prenyl lipid mannose galactose glucosamine inositol ceramide ethanolamine phosphatidylinositol * Myristoyl palmitoyl * Glycasyl phosphatidyl inositol anchor carboxyl * finean * Mouse lateral artifcially * * * Choline glycerol * Polar head,alkyl side ，steroids nucleus * Cholesterol phosphatidylcholine phosphatidylethanolamine * Aqueous cavity individual are cylindrical cross section of head equals that of side chain * Peripheral anchored cytoplasm * * Bilayer exterior surface interior cytosol * * * Heterotrophic photoautotrophic synthetic autotrophs * Catabolism containe nutrient precursor macromolecules nitrogenous phosphate * * Percent membrane lipid,cholesterol, * Phosphoglycerides choline ethanolamine inositol candiolipin diphosphatidyl glycerol * Sphingosine sphingomyelin moiety blue highlighted * saturated * Galactosylglyceride，glucocerebroside choline ethanolamine sphingosine ① 接合蛋白复合物AP2被募集到质膜内侧，停靠在synptotagmin上； ② AP2在质膜内侧自动群集，并募集网格蛋白三叉辐射体组装成网格状结构； ③ dynamin(发动蛋白参与披网格蛋白小泡形成的发动蛋白是一种胞质溶胶蛋白,有900个氨基酸, 能够同GTP结合并将GTP水解。发动蛋白的作用是在被膜小窝的颈部聚合,通过水解GTP调节自 己收缩, 最后将小泡与质膜割开。发动蛋白是一种G蛋白, )被募集到AP2-网格蛋白网格上，弯曲，形成有被小窝； ④ 受体自动聚集到有被小窝（有的受体在