[医学微生物学]肝炎病毒调研报告.ppt

教学笔记 教学笔记 * 16 我国每年有33万人死于因乙肝诱发的病变。这个数字，远远超过艾滋病和禽流感的死亡人数。但是显然，由于宣传的力度和外来的压力，政府对后者更为重视。 Slide *. HCV Life Cycle HCV在细胞内复制从HCV病毒颗粒与肝细胞膜上特异性受体的结合开始。The intracellular replicative mechanisms of HCV are thought to begin when the HCV virion binds to specific receptors on the hepatocyte surface and subsequently enters the host cell by means of endocytosis. The liver is considered to be the major, if not the only, site of replication of HCV. After uncoating the nucleocapsid, the virus undergoes translation and polyprotein processing. Once the viral core has been enveloped by mature proteins, the viru