BCC培训关联精编.pptVIP

全基因组关联分析;*;全基因组关联研究;遗传变异的检测;遗传变异的数量;SNP和SNP基因型;表型 模型和算法;编码基因型;病例/对照设计的数据结构;遗传假设和遗传模型;Dominant model Hypothesis: the genetic effects of AA and Aa are the same;Recessive model Hypothesis: the genetic effects of Aa and aa are the same ;Allelic model Hypothesis: the genetic effects of allele A and allele a are different ;卡方检验;Chi-squared test statistic: O is the observed cell counts E is the expected cell counts, under null hypothesis of independence ;R code Statistics - rchisq(1000, df = 5) hist(Statistics, prob=T) curve( dchisq(x, df=5), col=blue, add=TRUE ) curve( dchisq(x, df=2), col