线粒体钙超载幻灯片.pptVIP

Calcium Homeostasis and Calcium Overload in Cell(细胞内钙稳态与钙超载)Pathophysio. Dep. Of SDU袁中瑞 In all eukaryotic cells, the cytosolic concentration of Ca2+ ions ([Ca2+ ]C) is tightly controlled by interactions among transporters, pumps, channels and binding proteins. Finely tuned changes in [Ca2+ ]C modulate a variety of intracellular functions ranging from muscular contraction to secretion, and disruption of Ca2+ handling leads to cell death. 细胞内钙稳态调节 (Calcium Homeostasis in Cell 细胞内钙超载 (calcium overload in cell )