嵌入式超薄碳糊电极构建和应用.pdf

研究了目前常用的止血药酚磺乙胺ETA和人类中枢神经重要的神经递质多巴胺DA 在以主要成分为镍铬钼合金的316L不锈钢为基体的预阳极化超薄碳糊电极 f316L．PAIUCPE)上的电化学的反应行为，解释了支持电解质的影响，探究了溶液酸度对 其还原峰电流影响的作用机理。二者的氧化峰重叠，但是二者的还原峰电位差AEp为 140mV，基于此建立了一种同时测定ETA和DA的方法。在最优实验条件下，有一个 良好的线性关系在ETA和DA的氧化峰电流与其浓度分别在7．0×10～～2．0×10。4 mol·L。 和6．0×10—7~2．0x10‘4的范围之间，检出限分别为9．7x10一m01．L。1和9．2×10～mol·L～。该电 极表现出良好的重现性和高稳定性，可运用于实际样品酚磺乙胺注射液和盐酸多巴胺注 射液的分析检测。 关键词：316L不锈钢电极，预阳极化超薄碳糊，对氨基酚，对乙酰氨基酚，鸟嘌呤 ABSTRACT At present，the chemical modified carbon paste electrodes has gradually gained its wide applications on biological analysis，pharmaceutical analysis，organic analysis and environmental detection and SO on．In this paper,the matrix of the nickel chromium molybdenum alloy was adopted as a substrate to prepare the pre—anodized ultrathin carbon paste electrode by embedded on the surface of carbon paste and by cyclic voltammetric method in the solution ofO．20 mol／L NaOH，and research works are as following： 1．The simultaneous determination ofp-aminophenol，acetaminophen and guanine on the pre—anodized ultrathin carbon paste electrode based the nickel chromium molybdenum alloy In this papeg a pre—anodized inlaying ultrathin carbon paste electrode was prepared on the basis of 3 1 6L stainless steel scraps(3 16L—PAIUCPE)with a simple and rapid method．According to the relationship between the charge properties of the electrode surface active group，the formation and catalysis ofhydrogen bonds，the degree of reduction reaction on the auxiliary electrode，molecular configuration，the distribution fraction of different shapes and oxidation peak potential with solution acidity,it discussed the effect of pH on the corresponding oxidation peak current of p—AP,ACOP and G in detail．The effect of the supporting electrolyte on peak current of them was also discussed．Under the optimum conditions，the oxidation peak current was proportional to thep—AP,ACOP and G concentrations in the range of6．0×10—7_2．0×10一mol·L～． 8．0x10-7_3．5x10～m01．L～and 2．0x10-7 1．0x10一m01．L．1 with the detection limits of 7．86