龙血竭胶囊治疗糖病足溃疡的临床分析.docVIP

龙血竭胶囊治疗糖尿病足溃疡的临床分析 重庆市石柱土家族自治县人民医院内一科 吴斌 黄婷婷 杨纪才 向大兰 Clinical analysis of Resina Draconis capsule in the treatment of diabetic foot ulcer WU Bin HUANG Ting Ting YANG Ji Cai XIANG Da Lan (Shizhutujia nationality autonomous county peoples hospital , chongqing , 409100) [Abstract] Objective To observe the clinical effect of Resina Draconis topical and oral treatment of diabeticfoot ulcer. Methods 72 cases of diabetic foot patients,randomly divided into two groups. Systemic treatment with short acting insulin were subcutaneous injections before meals, long-term neutrul insulin injection once dailysubcutaneous injection of glucose control, Epalrestat, Alprostadil, statins, aspirin and debridement,anti infection therapy, treatment group was added with Resina Draconis capsules oral and Resina Draconis capsule contentamount of topical in the affected area. Evaluation of patients with clinical changes before and after treatment.Results Before treatment, two groups of patients withsimilar clinical symptoms were observed 8 weeks after thetreatment, clinical symptoms of two patients wereimproved, the total effective rate of treatment group 86.5%, control group, the total efficiency of 62.9%,P0.05. The curative effect of treatment group was better than the control group. Conclusion Resina Draconis topical and oral treatment of diabetic foot ulcers can promote woundhealing. Keywords:Resina Draconis; diabetic foot；ulcer; 【摘要】 目的 观察龙血竭外敷及口服治疗糖尿病足溃疡的临床疗效。方法 选择糖尿病足患者72例，随机分为两组。全身治疗均用短效胰岛素分别三餐前皮下注射，长效胰岛素注射液每天一次皮下注射控制血糖，用依帕司他、前列地尔、他汀、阿司匹林及清创、抗感染等治疗基础上，治疗组加用龙血竭胶囊口服及用龙血竭胶囊内容物适量外敷于患处。治疗前后评估患者临床变化。结果 治疗前两组病人临床症状相似，治疗观察8周后两组病人临床症状均有所改善，治疗组总有效率86.5％，对照组总有效率62.9％，P0.05。治疗组疗效明显优于对照组。结论 龙血竭外敷及口服治疗糖尿病足溃疡具有促进疮面愈合的作用。 关键词：龙血竭；糖尿病足；溃疡； 糖尿病足是糖尿病血管病变、神经病变和感染等因素导致糖尿病患者足或下肢组织坏死的一种病变。其主要临床表现为足部溃疡与坏疽，是糖尿病病人致残的主要原因之一，因其疗程长、花费高、预后差，给患者造成极大痛苦。临床治疗尤其在基层医院非常棘手。我科在常规治疗基础上加用云南版纳名盛制药厂生产的龙血竭外敷及口服治疗糖尿病足溃疡患者，疗效较好，现报道如下。 1 资料与方法 1．1 一般资料 治疗观察病例为2004年10月～2013年6月在我科住院治疗的糖尿