术前直肠上动脉栓塞术联合腹腔镜技术对直肠癌根治术的临床应用研究.docVIP

术前直肠上动脉栓塞术联合腹腔镜技术对直肠癌根治术的临床应用研究 　　【摘要】 目的：通过对比直肠癌患者术前运用直肠上动脉栓塞术联合腹腔镜方式或开腹方式实施直肠癌根治术的术后肿瘤复发转移情况，分析直肠上动脉栓塞术联合腹腔镜下直肠癌根治术的临床意义。方法：选择笔者所在科同期治疗的直肠癌患者80例，随机分为四组，A组常规开腹组，B组常规开腹联合术前直肠上动脉栓塞组，C组常规腹腔镜组，D组常规腹腔镜联合术前直肠上动脉栓塞组。分别对比各组患者的CEA含量变化及肝脏影像改变。结果：A与B组之间、C与D之间术中、术后CEA含量比较差异有统计学意义（P0.05）。A与B组之间、C与D之间术后12个月B超肝转移率比较差异有统计学（P0.05）。结论：术前直肠上动脉栓塞术联合腹腔镜下直肠癌根治术可以实现患者微创治疗的同时降低其术后近期CEA的浓度及增长速度，从而对降低肿瘤的血运转移存在意义。 　　【关键词】 直肠上动脉栓塞术； 腹腔镜； 直肠癌根治术 　　中图分类号 R735.3 文献标识码 A 文章编号 1674-6805（2014）17-0001-03 　　【Abstract】 Objective：To compare postoperative tumor recurrence and metastasis of colorectal cancer patients with preoperative rectal artery embolization combined with conventional laparoscopic or conventional laparotomy colorectal cancer resection，to analyze the clinical significance of rectal artery embolization combined with laparoscopic colorectal cancer resection.Method：80 cases with colorectal cancer in author’s department over the same period were randomly divided into four groups，group A（conventional laparotomy group），group B （conventional laparotomy combined with preoperative rectal artery embolization group），group C（conventional laparoscopic group） and group D（conventional laparoscopic combined with preoperative rectal artery embolization group）.The CEA levels changes and liver imaging changes of four groups were compared.Result：The content of CEA during and after the operation between group A and group B，and between group C and group D，were statistically significant（P0.05）.B-ultrasound detection rate of liver after 12 months of operation between group A and group B，and between group C and group D，were statistically significant（P0.05）.Conclusion：Preoperative rectal artery embolization combined laparoscopic colorectal cancer resection can reduce the recent CEA concentration and the growth rate while achieved minimally invasive treatment，thereby reduces the blood supply to the tumor metastasis. 　　【Key words】 Rectal artery embolization； Laparoscopic； Colorectal cancer resection 　　F