乳癌四分之一野与单中心技术详解.doc

1.文章在90年代初出现（国内2000年后），03年参加放疗标准化临床试验，06、08、09年还有技术改进文章 (Published Online?August?21?2006)Original Article An evaluation of three tangential breast irradiation techniques in Hong Kong Maria Y.Y.?Law?a1c1, Fion W.K.?Cheung?a1, Vincent W.C.?Wu?a1, Venus W.C.?Tsang?a1, Rainnie W.Y.?Kwan?a1, Johnny Y.T.?Cheng?a1 and Fatson K.F.?Wong?a1a1 Department of Optometry and Radiography, Hong Kong Polytechnic University, Hong Kong Article?author?query law my?? [PubMed] [Google Scholar]? cheung fw?? [PubMed] [Google Scholar]? wu vw?? [PubMed] [Google Scholar]? tsang vw?? [PubMed] [Google Scholar]? kwan rw?? [PubMed] [Google Scholar]? cheng jy?? [PubMed] [Google Scholar]? wong fk?? [PubMed] [Google Scholar]? Abstract Background and Purpose: Loco-regional radiotherapy after breast conserving surgery significantly reduces the risk of recurrence but may induce complications in the lungs. The complications are related to the lung volume irradiated and the lung dose delivered. The purpose of this study was to evaluate three tangential breast irradiation techniques i.e. conventional technique, gantry tilting technique and half-beam block technique in terms of the percentage of irradiated lung volume and high dose lung volume for patients of different sizes. Materials and Method: Treatment planning of the three tangential breast irradiation techniques was performed using the CT scans of 20 patients with early-stage breast cancer after lumpectomy. Results: When compared with conventional technique, both half beam block technique and gantry tilting technique irradiated a significantly smaller percentage of lung volume and delivered a smaller percentage of high dose (above 30 Gy) volume in the lung. Patients with large breasts had a significantly higher percentage of lung volume irradiated to above 30Gy than those patients with small and medium breasts. The combined effect of tangential separation and technique only produced significant effect on the percentage