increasesAβsecretionHA-taggedfulllengthSUMOisoforms.pptVIP

SUMO3 overexpression increases Aβ secretion HA-tagged full length SUMO isoforms SUMO1, 2 and 3 were co-transfected with APPwt in HEK-293 cells. Véronique Dorval et al. Biochem. J. 2007;404:309-316 ?2007 by Portland Press Ltd SUMO3 overexpression increases Aβ secretion HA-tagged full length SUMO isoforms SUMO1, 2 and 3 were co-transfected with APPwt in HEK-293 cells. A Cells were harvested, lysed and equal amounts of proteins were analysed by Western blot analysis. SUMO expression and conjugation was visualized using an anti-HA antibody. SUMO monomers arrow and the high molecular mass