IL-2,IL-7,IL-15,andIL-21causedose-dependentaugmen.pptVIP

IL-2, IL-7, IL-15, and IL-21 cause dose-dependent augmentation of in vivo antitumor treatment mediated by adoptively transferred CD8+ T cells. Christopher A. Klebanoff et al. Clin Cancer Res 2011;17:5343-5352 ?2011 by American Association for Cancer Research IL-2, IL-7, IL-15, and IL-21 cause dose-dependent augmentation of in vivo antitumor treatment mediated by adoptively transferred CD8+ T cells. Dose of exogenously administered γc-signaling cytokines correlates with the slope of tumor regression mediated by adoptively transferred CD8+ T cells. The slope of tumor regression mm2/d for indi