肺保护机械通气seminar2008a.ppt

Ventilator Induced Lung InjuryVILI Overdistention Barotrauma Volutrauma Recruitment/Derecruitment Injury Translocation of Cells Biotrauma Overdistention Barotrauma Volutrauma VILI： Recruitment/Derecruitment Injury Translocation of Cells Translocation of Cells disrupt the alveolar epithelium tears in capillary endothelium Arthur S Slutsky Serum Cytokines in Acid Aspiration ModelChiumello, Pristine, Slutsky AJRCCM 1999;160:109-16 Cytokines in HumansStuber et al Int Care Med 2002;28:834-841 ARDS Mortality Decreased Abruptly Shanghai ARDS Study Group. 15 ICUs in 12 universit