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A shift-invariant morphological system for software development cost estimation??Original Research ArticleExpert Systems with Applications It is an important aspect that rapid prototyping technique can be used into tissue engineering. Biomimetic porous scaffolds made of calcium phosphate mineral are promising structures to develop bone substitute. Bone tissue engineering scaffold characteristics and properties are often considered to be critical factors in their design and fabrication. In this paper according to their demand, some scaffolds were introduced and designed with Computer Aided