SYNTAXS core对于无保护左主干病变冠状动脉疾病的冠状动脉介入治疗之后的用途.doc

SYNTAXS Score对于无保护左主干病变冠状动脉疾病的冠状动脉介入治疗he SXscore has been recently developed as a combination of several previously validated angio- Graphic classifications aiming to grade the coronary anatomy with respect to the number of lesions and their functional impact, location, and complexity. Higher SXscores, indicative of a more complex condition, are likely to represent a bigger therapeutic challenge and to have a potentially worse prognosis in patients undergoing contemporary revascularization with (PCI). ClinicalPerspectiveonp308 The predictive value of the SXscore was recently validated on a series of patients undergoing PCI for 3-vessel coronary artery disease in the Arterial Revascularization Therapies Study Part II. However, a validation of this angiographic tool on a restricted series of patients with unprotected left main coronary artery disease undergoing PCI is lacking. We sought to address this issue by applying the SXscore in patients who underwent percutaneous treatment for left main disease in our institution to examine its prognostic value in predicting in-hospital and long-term clinical outcomes. The performance of the SXscore was also explored in comparison with the modified lesion classification system of the American Heart Association/American College of Cardiology (AHA/ACC). Methods Patient Population All consecutive patients undergoing PCI with either a sirolimuseluting stent (Cypher, Cordis, a Johnson and Johnson Company, Miami Lakes, Fla) or a paclitaxeleluting stent (Taxus, Boston Scientific, Natick, Mass) in left main coronary artery, from January 2003 to June 2008, at the Ferrarotto Hospital, Italy, were evaluated in this single-center study. The clinical outcome of a number of these patients was reported previously. The left main coronary artery was defined as unprotected if there were no patent coronary artery bypass grafts to the left anterior descending artery or left circumflex artery. A percutaneous approach rather than a surgical one