感染伤口的处理介绍.ppt

* Elastase is a collagen degrading protease and an important virulence factor in the wound pathogen Pseudomonas aeruginosa. This is one of the reasons why P aeruginosa delays wound healing. * Yet another important virulence strategy, that has been recognized lately also for bacteria colonizing wounds, is the ability of bacteria to form so called biofilms. Biofilm is composed of microorganisms enclosed in slime made of polysaccharides. Both our own immune system and antimicrobial agents have poor effect on bacteria within biofilms. It is believed that the slime inhibit penetration of antimicrob