20131230-蛋白质组学及生物信息学教程范本.ppt

* One-dimensional gels (for example, analysis after affinitypurification)Two-dimensional gels (for example, analysis after affinitypurification, body fluids, etc.)Protein chips (chips coated with, for example, proteins orantibodies)Proteins/protein complexes in solution (identificationwithout electrophoresis) * ★蛋白质三维结构和相关数据库1. PDB /pdb/是美国Brookhaven实验室的大分子结构数据库，主要是通过X射线晶体衍射、核磁共振等手段测定的生物大分子的三维结构，也包括了核酸、糖类、蛋白质与核酸复合物的三维结构。 截至2012/10/16，已含有约85435个结构，90%是蛋白质结构。(Macromolecule databse of Brookhaven, including the structures of proteins from X-ray, NMR and others, also including 3-D structures