Discoering the Chemical Nature of the Gene.pptVIP

Discovering the Chemical Nature of the Gene The first scientist to investigate the question of how genes affect phenotype was Sir Archibald Garrod, whose studies of alkaptonuria implied a relationship between genes and enzymes. Thirty years later Beadle and Ephrussi showed a relationship between particular genes and biosynthetic reactions responsible for eye color in fruit flies. Next, in a series of classic experiments on the effects of mutations in the bread mold Neurospora crassa, Beadle and Tatum explored the one-gene-one-enzyme hypothesis-the idea that each gene codes for a particular