八级杆工作原理(ICP-MS).pptVIP

Choose View, Header and Footer to enter text here What is a Collision/Reaction Cell? The Octopole Reaction System (ORS) is an octopole ion guide contained within a stainless steel vessel and pressurized with a gas, most often H2 or He. The ORS is positioned between the ion lens assembly and the quadrupole mass filter. As ions from the sample enter this cell, they interact with the gas, resulting in the reduction of the molecular interference normally below the level of the blank solution. Eliminates key interferences arising from the sample matrix that are not argon based and cannot be eliminated using “traditional” approaches. Why use an Octopole? (1) Why use an Octopole? (2) Processes in the Cell ORS can be operated without using highly reactive gases. Octopole design allows higher cell pressures increasing reaction cross section due to better ion beam focussing He Mode Collisionally Induced Dissociation – the interference is broken apart when it impacts the He atom Energy Discrimination – the larger polyatomic species (greater ionic radii) loose more energy than the smaller analyte species and cannot enter the QP – effectively a molecular filter Aided by the Agilent ShieldTorch System – all ions enter the Octopole with well-defined narrow energy distribution H2 Mode Charge Transfer – electron transferred from (or to) hydrogen, producing a neutral species Actually both modes use Energy Discrimination, at least in part Collisionally Induced Dissociation (CID) Helium Mode Energy Discrimination – Ionic Radii Energy Discrimination – Ionic Radii Energy Discrimination (ED)Helium Mode ED CID In Action 7500c Tune Screen Charge TransferHydrogen Mode Reaction Mode 7500c Tune Screen How Does the Reaction Cell Work? Featuring the Agilent Octopole Reaction System = analyte ion Octopole Reaction System Initial Ion Energy Energy After Collision Small diameter Ions entering the reaction cell have an ion energy in the radial direction corresponding to the dotted line labe