染色体病(林蓉)2016讲义.ppt

* * 周一讲到这 Zhouer4-5 * * Ring chromosomes: vicious circles at the end and beginning of life David Gisselsson, Ph. D. Figure 1 Giemsa-Trypsin-Giemsa banding and ideogram results show autosomal-balanced reciprocal translocation involving chromosomal regions 8q and 18q. The arrows indicate the breakpoints on derivative chromosomes 8 and 18. (B) Fluorescence in situ hybridization of metaphase spread with the Vysis WCP DNA probes, which hybridize chromosome 8 (Spectrum Green) and chromosome 18 (Spectrum Red). The arrows indicate the derivative chromosomes 8 and 18. (C) Pedigree demonstrates charact