双j管 2009-不同类型的双J管.docVIP

双j管 2009-不同类型的双J管 Lingeman et al.Page 2 patient discomfort.1–5 With the introduction of the Ureteric Stent Symptoms Questionnaire (USSQ) (? Stone Management Unit, Southmead Hospital, UK) USSQ in 2003, a standardized instrument became available for use in clinical trials evaluating patient comfort after stent placement.6,7 Validation of the USSQ in the United Kingdom was conducted in a clinical trial setting comparing symptoms of stented and non-stented patients who were evaluated at 1 and 4 weeks after stent placement and 4 weeks after stent removal, timing that was consistent with standard practices in the UK. Near-term (lt; 1 week) comfort was not assessed in the USSQ validation study. Until recently, near-term comfort had not been assessed in a large clinical population involving comparison of multiple stent types. Herein, we examine the hypothesis that substituting the distal pigtail end of a ureteral stent with Short or Long Loop Tail designs would enhance patient comfort by reduced mass and material in situ. The USSQ was utilized in this study and we secondarily evaluated it as a tool for assessing stent discomfort.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptMATERIALS AND METHODSThis was a prospective, 4-arm, multicenter study comparing stent-related comfort amongpatients ≥ 18 years of age who had undergone an uncomplicated ureteroscopy requiringretrograde unilateral placement of a ureteral stent for 4 – 28 days (inclusive). Exclusioncriteria for the study included: active urinary tract infection, urinary malignancy, non-stonerelated pain or stricture, spinal cord injury, bilateral stent placement, or patients chronicallytaking anti-inflammatory medications. Patients provided signed informed consent prior tostudy entry at study centers approved by local institutional review boards.The study was designed to compare differences in patients’ ureteral stent-related comfortassessed via the patient self-administered USSQ. The U