心肺复苏低温治疗资料.ppt

Therapeutic hypothermia in Post–Cardiac Arrest Care 2015 VS 2010 hypoxemia ischemia reperfusion multiple organ systems 低温治疗的分类 低温治疗作用机制的新观念 降低脑的代谢水平,减低氧耗,改善并恢复能量供给; 抑制氧自由基产生,减轻氧化应激损伤; 下调炎症介质的产生和炎症细胞的集聚,减轻炎症损伤; 减低神经细胞及心肌细胞凋亡。 IntensiveCareMed.1996,22(11):1191-6. The 2010 Guidelines advised hypothermia duration temperature 12 to 24 hours The 2015 Guidelines advised hypothermia (32oC to 36oC) 2015 Guidelines advised hypothermia at least 24 hours (cerebral performance category,CPC) 脑功能功能分类 敏感性较差 1. 好

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