经验性抗菌药物治疗的原则与策略巩路(济南10221).pptVIP

* * * Slide * The core organisms for group 1 include S. pneumoniae, methicillin-sensitive S. aureus (MSSA), H. influenzae, and enteric gram-negative bacilli. The ATS recommends monotherapy for HAP patients in this group, including second-generation cephalosporins, a ?-lactam/?-lactamase inhibitor combination (piperacillin/tazobactam, ticarcillin/clavulanate), or a non-pseudomonal third-generation cephalosporin (cefotaxime or ceftriaxone). A fluoroquinolone, or clindamycin plus aztreonam, may be considered for penicillin-allergic patients, provided that S. pneumoniae is ruled out. * Slide *