cancer in 15 to 29yearolds by primary site.docVIP

Cancer in 15 to 29YearOlds by Primary Site nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 作者：Archie Bleyera, Aaron Vinyb, Ronald Barrcnbsp;nbsp; 【关键词】nbsp; Adolescent,and,young,cancer nbsp; a Cancer Treatment Center, St. Charles Medical Center, Bend, Oregon, USA; b Clevelend Clinic Lerner College of Medicine, Cleveland, Ohio, USA; c Department of Pediatrics, Pathology, and Medicine, McMaster University, Hamilton, Ontario, Canada nbsp; Key Words. Adolescent and young cancer ; Epidemiology ; Risk factors nbsp; ABSTRACT nbsp; Incidence. Cancer occurring between the ages of 15 and 30 years is 2.7 times more common than cancer occurring during the first 15 years of life, yet is much less common than cancer in older age groups, and accounts for just 2% of all invasive cancer. Cancer in adolescents and young adults is unique in the distribution of the types that occur. Hodgkin lymphoma, melanoma, testis cancer, female genital tract malignancies, thyroid cancer, soft-tissue sarcomas, non-Hodgkin lymphoma, leukemia, brain and spinal cord tumors, breast cancer, bone sarcomas, and nongonadal germ cell tumors account for 95% of the cancers in this age group. The frequency distribution of cancer types changes dramatically from age 1530, such that the pattern at the youngest age does not resemble the one at the oldest. The incidence of cancer in this age group increased steadily during the past quarter century. This increase is declining and at the older end of the age range appears to be returning to the incidence of the 1970s. Males in the 15- to 29-year age group have been at higher risk of developing cancer, with the risk directly proportional to age. Non-Hispanic whites have had the highest risk of developing cancer during this phase of life, and Asians, American Indians and Native Alaskans the lowest. Males had a worse prognosis than females. African-Americans, American Indian/Alaska Natives had a worse p