不同方法对糖耐量减低干预效果的比较研究.docVIP

不同方法对糖耐量减低干预效果的比较研究 nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp; 作者：刘鹏鹰 刘君英 彭绩 熊静帆 肖洁 李瑛 邬磊 黄耀辉nbsp; 【摘要】nbsp; 目的：比较不同干预方法对糖耐量减低的影响。方法：选取深圳市五个区 IGT 患者各 100 例，按照干预方案再分为对照组、饮食加运动组、阿卡波糖组、二甲双胍组和中药组各 100 例。分别于干预前后测定 BMI、SBP、DBP、 FPG、2hPG、HbA1C。结果：饮食运动组干预后 FPG、2hPG 与对照组干预后比较差异有统计学意义（P lt; 0.05）；阿卡波糖及二甲双胍组干预后 FPG、2hPG、HbA1C 均明显低于干预前、对照组、饮食运动组及中药组，其差异有统计学意 义（P lt; 0.05）；中药组 FPG、2hPG 明显低于干预前及对照组，HbA1C 低于对照组和饮食运动组，其差异有统计学意义（P lt; 0.05）。结论：上述 4 种方法均有效降低血糖，尤以西药组突出。 【关键词】nbsp; 糖耐量减低；生活方式；药物；干预研究 nbsp;nbsp;nbsp; Thenbsp; Comparativenbsp; Studynbsp; ofnbsp; Interventionnbsp; Effectnbsp; bynbsp; Differentnbsp; Methodsnbsp; onnbsp; thenbsp; Populationnbsp; withnbsp; Impairednbsp; Glucosenbsp; Tolerance nbsp;nbsp;nbsp; 〔Abstract〕 Objective Tonbsp; evaluatenbsp; thenbsp; effectnbsp; ofnbsp; differentnbsp; methodsnbsp; onnbsp; thenbsp; populationnbsp; withnbsp; impairednbsp; glucosenbsp; tolerancenbsp; (IGT).nbsp;nbsp;nbsp; Methodsnbsp;nbsp;nbsp;nbsp; Thenbsp; totalnbsp; ofnbsp; fivenbsp; hundrednbsp; IGTnbsp; patientsnbsp; werenbsp; dividednbsp; intonbsp; fivenbsp; groupsnbsp; accordingnbsp; tonbsp; interventions.nbsp; BMI,nbsp; SBP,nbsp; DBP,nbsp; FPG,nbsp; 2hPG,nbsp; HbA1Cnbsp; werenbsp; determinednbsp; beforenbsp; interventionnbsp; andnbsp; yearlynbsp; duringnbsp; thenbsp; follownbsp; up.nbsp;nbsp;nbsp; Resultsnbsp;nbsp;nbsp;nbsp; Bynbsp; thenbsp; endnbsp; ofnbsp; thenbsp; study,nbsp; althoughnbsp; thenbsp; FPGnbsp; andnbsp; 2hPGnbsp; slightlynbsp; decreasednbsp; innbsp; dietnbsp; plusnbsp;nbsp; exercisenbsp; group,nbsp; theynbsp; werenbsp; significantlynbsp; lowernbsp; thannbsp; thosenbsp; innbsp; thenbsp; controlnbsp; group.nbsp; Innbsp; contrast,nbsp; thenbsp; FPG,nbsp; 2hPGnbsp; andnbsp; HbA1C werenbsp; significantlynbsp; decreasednbsp; innbsp; Acarbosenbsp; andnbsp; Metforminnbsp; group.nbsp; Innbsp; traditionalnbsp; Chinesenbsp; medicinenbsp; group,nbsp; thenbsp; FPGnbsp; andnbsp;nbsp; 2hPGnbsp; werenbsp; si