【2017年整理】400t红霉素生产工厂的初步设计.doc

400 t/a 红霉素生产工厂的初步设计 专业：生物工程 摘 要：课程设计是重要的实践教学环节, 在实践教学中起到承上启下的作用, 可为学生毕业后到工厂工作打下良好的工作基础。本设计是为年产300t红霉素而进行的初步工艺设计。根据毕业设计大纲和设计任务要求该设计分别对各工艺作了详细阐述，以理论计算为依据，以实际工厂设计为参考，力求接近并切合实际。其主要包括生产工艺的各种指标、设备选形设计计算、物料衡算、水、电、汽的估算以及工艺流程图的设计。该设计成果主要采用形式为全厂总平面布置图（1张），工艺流程图（1张），设备布置图（1张），并编写详细数据说明书。 关键词：红霉素；工艺流程; 设计 An Initial Technological Design for Erythromycin with year Output of 4000 ton Major: Biology Engineering Author: Fu Xiangke Supervisor: Li Huidong (School of Life Sciences Hunan University of Science and Technology Abstract：The Fermentation Engineering and Equipment Course Design can play the connecting role between the preceding and the following in the practice teaching, and lay a good foundation for the students to work in the factory after graduation. This subject is an initial technological design for Erythromycin with year output of 300 ton.According to the requirement,the process of erythromycin production and the calculation of the mass balance and heat quantity balance are completed. In this subject , all of theprocesses are expounded in detail. All the contents are based on the academic calculations .we refer to the practical designes in companies and make our best to approach to the practice. it mainly includes the production craft each kind of target,the equipment chooses the shapedesign calculation,material of the graduated arm of a steelyard calculation,the water,the electricity,the steam estimate as well as the flow chart design.This designachievement mainly uses the form for the entire factory totalfloor-plan(1),flowchat(1),equipment general arrangement(1),and compilation particular data instruction booklet.. Key word: Erythromycin; Process; Design  1 绪论 1.1 红霉素的理化性质 红霉素（Erythromycin）分子式及结构式 ：C37H67O13N 分子量：733.94 g/mol 结构：红霉素是由红霉内酯与去氧氨基己糖和红霉糖缩合而成的碱性苷。红霉内酯环含有13个碳原子，内酯环的C-3通过氧原子与红霉糖相联结，C-5通过氧原子与去氧氨基己糖相连接。红霉糖本身不含氮，是含有 一个甲氧基的己糖，去氧氨基己糖。 成分：由链霉素Streptomycin elytrous所产生，是一种碱性抗生素。其游离碱供口服用，乳糖酸盐供注射用。此外，尚有其琥珀酸乙酯（琥乙红霉素）、丙酸酯的十二烷基硫酸盐（依托红霉素）供药用。 1.1.1名称分类： 别名：威