2015年的clsi更新要点.docVIP

下载本文档

10
0
约3.62万字
约 34页
2017-01-19 发布于北京
举报
版权申诉

2015年的clsi更新要点.doc

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

What’s New in the 2015 CLSI Standards for Antimicrobial Susceptibility Testing (AST) ? Janet A. Hindler, MCLS MT(ASCP) UCLA Health System jhindler@ “and consultant with the Association of Public Health Laboratories” 1 Objectives ? Identify the major changes found in CLSI document M100-S25, M02-A12, M07-A10. ? Design a strategy for implementing the new guidelines into your laboratory practices. ? Develop a communication strategy for informing clinical staff of significant AST and reporting changes. Please check supplemental materials posted for this webinar: ? Self study program ? Implementation Checklist 2 CLSI AST Standards January 2015 ? M100-S25 Tables (2015)1 ? M02-A12 Disk Diffusion Method (2015)2 ? M07-A10 MIC Method (2015)2 ? M11-A8 Anaerobe MIC Testing (2012) 1 M100 updated at least yearly 2 M02, M07 updated every 3 years 3 Major Changes 2015 M100-S25 ? General – Introduced Epidemiological Cutoff Value (ECV) ? Enterobacteriaceae – Salmonella ? Added pefloxacin disk diffusion test to differentiate isolates “S” vs. “not susceptible” to fluoroquinolones ? Added azithromycin disk diffusion and MIC tests for S. Typhi ? Enterobacteriaceae, P. aeruginosa, Acinetobacter – Added Carba NP test for detection of carbapenemases 4 Summary of Changes M100-S25. p. 13-15. 5 Major Changes 2015 M02-A12; M07-A10 ? Formatting – Labeled main sections as “chapters” – Summarized content in “chapters” – Added “step-action tables” – Added “flow charts” ? Brought up to date with M100 (updated annually) ? Content – Staphylococcus spp. – expanded discussion of tests to detect oxacillin resistance – Quality control ? Several new flow charts 6 “Chapter” Example Disk Diffusion Testing Process M02-A12. p. 15. “Step-Action” Table Example Inoculate Disk Diffusion Plates 7 Determine need for susceptibility testing (Chapter 2) “Flow Chart” Example MIC Susceptibil