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* * * * * * * * * * * * * * * * * * * * The rest of the talk today will be making sense of this. * * * * * * * * * * * * * * * * * * * * * * * * * * * * Applications Prediction of protein structure and function Design of small molecules to augment or inhibit biological function Analysis of complex genetic phenomena Design of modified macromolecules for medical or industrial uses Understanding how genetic factors contribute to host susceptibility to disease ( pathogenicity of infectious agents) Recent Explosive Growth Emergence of the genome sequencing projects (GENBANK, EMBL) Large scale data collection efforts in biology (Protein Data Bank) The Human Genome Project Potential Applications Pharmaceutical industry New therapeutic and diagnostic approaches Cancer research Clinical Bioinformatics Sequence information will routinely be stored in the medical records in next 5 to 10 years Lessons learned in the creation and maintenance of biological genetic databases will be useful in electronic medical record Genetic background of patients is a critical element of patients’ past medical history Tracking of infectious disease and optimal antibiotics treatment will be driven by genetic features of the pathogens Clinical Informatics 10. Barriers to clinical system implementation11. Clinical systems in ambulatory care12. Clinical systems in high intensity care13. Careflow and process improvement systems14. Disease management15. E-health and clinical communication16. Evaluation of health information systems17. Health data warehousing18. Health information systems19. Integrated health and financial systems Education and Training 20. Computer-assisted medical education21. Consumer health information22. E-learning or distance learning23. Education and training24. Library information systems25. Medical informatics teaching26. Patient education and self-care27. Professional education Human Information Processing and Organizational Behaviour 28. Cognitive models
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