(右归胶囊学术301课题结果.docVIP

右归胶囊治疗男性弱精症的临床疗效观察 何学酉＊ 吴意光＊ 王春杨 张旭 （中国人民解放军总医院泌尿外科， 北京 100853） 【摘要】 目的： 探讨右归胶囊对弱精症患者精子存活率及活力的影响。 方法： 2009年4月～2010年5月在门诊就诊的不育患者中，将弱精症患者80例随机分为治疗组和对照组，分别服用右归胶囊和五子衍宗丸，治疗周期三个月。治疗前后,运用WLJY-9000伟力彩色精子质量计算机辅助精液分析系统(CASA)检测精子密度、活力。以改良巴氏色法将精子染色后运用CASA检测精子形态变化。结果： 右归胶囊治疗组精子存活率及活力均较治疗前明显提高（P＜0.05），且与对照组比较有显著性差异。结论： 右归胶囊可提高弱精症患者的精子存活率及活力，疗效优于五子衍宗丸。 【关键词】 弱精症；中医药疗法 中图分类号 R698.2 R283.65 Clinical efficacy of Yougui Capsule and Wuziyanzong Pill on patients with oligoasthenospermia He Xueyou, Wu Yiguang, Wang Chunyang, Zhang Xu Department of Urology, Chinese PLA general hospital, Beijing, 100853, China Abstract Objective To investigate the clinical effect of the Chinese traditional medicine Yougui Capsule and Wuziyanzong Pill on the patients with oligoasthenospermia. Methods A total of 80 male patients with infertility induced by oligoasthenospermia from April 2009 to May 2010 were equally divided into 2 groups randomly: treated group and controlled group, the former medicated with Yougui Capsule at the dose of 1.68 g, Tid, while the controlled group were given Wuziyanzong Pills at the dose of 6g, Bid, both for a course of 12 weeks. Then we analyzed the changes in the patients’ seminal parameters by WLJY-9000. Results After 12 weeks of medication, both the seminal parameters of the patients and pregnancy of their wives were remarkably improved, with extremely significant differences from pre-treatment and the control (P 0.05). Conclusion Yougui Capsule and Wuziyanzong Pill could improve sperm motility and vitality as well as sperm count. With few adverse effects, Yougui Capsule can be used as a safe and effective therapeutic for male infertility induced by oligoasthenospermia, and the effect was better than Wuziyanzong Pills. Key words oligoasthenospermia/traditional Chinese medicine and pharmacy therapy 近几十年来随着现代科技的发展，电子产品的日益普及以及化学添加剂的广泛使用，环境污染及不健康生活方式的影响，男性不育患者逐渐增多。在不育夫妇中，男性因素约占一半的比例。其中弱精症是最常见的类型。 引起精子活力低下的病因很多，包括感染、精液液化异常、精索静脉曲张、免疫、内