ppt课件-combinatorial optimization problemsin computational biology（在计算生物学组合优化问题）.pptVIP

Algorithms for Universal DNA Tag Array Design and Optimization Ion Mandoiu Computer Science Engineering Department University of Connecticut High-Throughput Assay Design Fast growing number of applications, with more stringent constraints on sensitivity, reproducibility, cost, etc. Source of challenging combinatorial problems Multiplex PCR primer set selection Probe selection Fidelity probes Mask design … This talk: design and optimization of universal tag arrays Overview Watson-Crick Complementarity DNA Microarrays Applications Gene expression (transcription analysis) Genomic-based micro