高血压指南和用药__培训课件.pptVIP

* 而中国，1991年的报道中国的高血压的抽样调查估计全国有已经有9400百万的高血压患者。而2000－2001年亚洲国际心血管病合作研究中全国35－74岁人口的大样调查，发现有约1.3亿的中国人患有高血压！也就是10个人中就有1个患有高血压。控制率仅8.1％只有美国的四分之一 * * In the MRFIT study, systolic BP was more strongly related to the risk of stroke than was DBP. For example, in the highest decile (≥151 mm Hg/≥98 mm Hg), the relative risk of stroke was 8.2 for systolic BP and 4.4 for DBP.1 1. He J, Whelton PK. Elevated systolic blood pressure as a risk factor for cardiovascular and renal disease. J Hypertens. 1999;17(suppl 2):S7-S13. * Elevated systolic BP correlates with an increase in the adjusted relative risk of end-stage renal disease (ESRD). For example, those in the highest systolic BP quintile (140 mm Hg) had 5 times the relative risk of developing ESRD compared with those in the lowest systolic BP quintile (117 mm Hg).1 1. He J, Whelton PK. Elevated systolic blood pressure as a risk factor for cardiovascular and renal disease. J Hypertens. 1999;17(suppl 2):S7-S13. * This shows the overall benefit of treatment. There are large reductions in deaths from stroke, CHD and vascular disease, but not increase in death from other causes. * Analyses for major CV events, CV mortality, and total mortality did not show significant differences among ?-blockers/diuretics, CAs, or ACE inhibitors.29 29. Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet. 2003;362:1527-1535. SLIDE * * When pooled, the outcomes data indicate that patients who were controlled, regardless of treatment regimen, had significantly better outcomes than those whose blood pressure was not controlled at 6 months.1 Early blood pressure control was a powerful determinant of almost all endpoints (except myocardial infarction).1 1. Weber MA et al. Blood pressure dependent and independent effects of antihypertensive treatment on clinical values in the