多灶性运动神经病要点.doc

Multifocal motor neuropathy 1. Clin Neuroradiol. 2015 Dec;25(4):423-5. doi: 10.1007/s00062-014-0364-9. Epub 2015 Jan 3. Ultrasonography of Multifocal Acquired Demyelinating Sensory and Motor Neuropathy (MADSAM). Neubauer C(1), Gruber H(2), B?uerle J(3), Egger K(4). Author information: (1)Department of Radiology, University Medical Center Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. (2)Department of Radiology, Innsbruck Medical University, Anichstra?e 35, 6020, Innsbruck, Austria. (3)Department of Neurology, University Medical Center Freiburg, Breisacher Str. 64, 79106, Freiburg, Germany. (4)Department of Neuroradiology, University Medical Center Freiburg, Breisacher Str. 64, 79106, Freiburg, Germany. karl.egger@uniklinik-freiburg.de. PMID: [PubMed - in process] 2. J Crohns Colitis. 2015 Dec;9(12):1174-5. doi: 10.1093/ecco-jcc/jjv137. Epub 2015 Jul 29. Multifocal Motor Neuropathy Associated with Infliximab. Rowan CR(1), Tubridy N(2), Cullen G(2). Author information: (1)Centre for Colorectal Disease, St Vincents University Hospital, Dublin, Ireland and School of Medicine and Medical Science, University College Dublin, Dublin, Ireland. c.rowan2@st-vincents.ie. (2)Centre for Colorectal Disease, St Vincents University Hospital, Dublin, Ireland and School of Medicine and Medical Science, University College Dublin, Dublin, Ireland. BACKGROUND: The anti-tumour necrosis factor [TNF] monoclonal antibody, infliximab, is commonly prescribed in both ulcerative colitis and Crohns disease. Neurological side effects such as optic neuritis are well recognised, although not as frequently seen as hypersensitivity and serious infections. CASE: We present a case of peripheral neuropathy in a young man on infliximab therapy for ulcerative colitis. This presented as an asymmetrical and slowly progressive weakness in his right upper limb, severely impacting on function. Investigations confirmed a diagnosis of multifocal motor neuropathy [MMN]. Thi