FLAIR和DWI在急性脑梗塞中的应用.docVIP

FLAIR和DWI在急性脑梗塞中的应用　【摘要】　目的：比较液体衰减反转恢复(FLAIR)序列和弥散加权成像(DWI)在急性脑梗塞中的应用。方法：14例急性脑梗塞患者接受FLAIR和DWIMR检查，评价病变的显示范围、边界及对比度，并计算病变区ADC和rADC。结果：FLAIR序列和DWI对病变的显示范围、对比均优于常规T2WI，以DWI对病变显示更佳，病变区的平均ADC为6.13×10－4mm2/s，rADC为56.47%。结论：FLAIR和DWI在急性脑梗塞中均有用，以DWI最好，且能对急性脑梗塞作定量评价。　　【关键词】　急性脑梗塞　磁共振成像　液体衰减反转恢复序列　弥散加权成像 MR assessment of acute cerebral infarction with FLAIR and DWI Xiao Xuehong,Kong Xiangquan,Jiang Li,et al.(Department of radiology,Xiehe Hospital of Tongji Medical University,Wuhan 430022) 　　【Abstract】　Purpose:To compare fluid-attenuated inversion-recovery (FLAIR) sequence and diffusion-weighted imaging (DWI) sequence in evaluation of acute cerebral infarction.Methods:14 cases of acute cerebral infarction were examined with FLAIR and DWI sequences on 1.5T MR scanner.The extent,boundary and contrast of the lesions on all images were evaluated.Apparent diffusion coefficient (ADC) and relative ADC(rADC) of the lesions were calculated.Results:The extent,boundary and contrast on FLAIR and DW images were superior to conventional T2WI.The visualization of the lesions on DW images was proved to be the best.The mean ADC and rADC of the lesions was 6.13×10－4mm2/s and 56.47% respectively.Conclusion:Both FLAIR and DWI sequences are more valuable on visualization of acute cerebral infarction than conventional T2WI sequence.DWI was the best to show the lesions,furthermore,it can assess the infarction area quantitatively.　　【Key words】　Acute cerebral infarction　MRI　FLAIR　DWI 　　液体衰减反转恢复(fluid-attenuated inversion-recovery,FLAIR) 序列通过对脑脊液的抑制，改善病变与正常组织间的对比，广泛用于包括急性脑梗塞在内的中枢神经系统疾病的诊断［1～4］；弥散加权成像(diffusion-weighted imaging,DWI)是近年发展起来的MRI新技术，它对脑缺血尤其是急性期脑缺血非常敏感［5～7］，与FLAIR的图像对比有部分相似之处，本文旨在比较弥散加权成像和FLAIR在急性脑梗塞中的应用价值。 材料和方法　　1. 一般资料　　急性脑梗塞患者14例，男9例、女5例，年龄48～73岁，平均58.7岁。发病至第一次MRI检查的时间8～40h，平均25h，经CT和/或MR检查排除脑出血。　　2. MR检查　　所有病例均在1.5T超导MR仪上进行，用头部正交线圈，常规SE或快速SE(TSE)序列平扫T1WI和T2WI，FLAIR用IR-TSE序列TR9000～9500ms，TE112ms，TI2500ms，回波链长为11，矩阵176×256，FOV17cm×23cm，一次信号平均；DWI采用SE序列T2加权的单次激发平面回波成像(EPI)，与颅底平行的横