原发性甲状旁腺功能亢进症15例外科治疗分析.docVIP

原发性甲状旁腺功能亢进症15例外科治疗分析 　　doi：10.3969/j.issn.1007-614x.2014.14.25 　　摘 要 目的：探讨原发性甲状旁腺功能亢进症的诊断和外科治疗经验。方法：回顾性分析2006-2013年行外科手术治疗的15例原发性甲状旁腺功能亢进症患者的临床表现、实验室检查和术前、术中定位方法及手术治疗方式。结果：15例患者中，术前联合B超、CT、核素扫描定位诊断准确。术后临床表现缓解，化验指标恢复正常，无永久性甲状旁腺功能减退或喉返神经损伤等并发症。结论：原发性甲状旁腺功能亢进症的诊断需结合临床症状和辅助检查，甲状旁腺切除术是治疗原发性甲状旁腺功能亢进症的有效方法，术前、术中的准确定位是手术成功的关键。 　　关键词 甲状旁腺功能亢进症 甲状旁腺肿瘤 外科手术 　　The analysis of the diagnosis and surgical treatment for patients with Primary Hyperparathyroidism 　　Zhao Song 　　The Basic Medical department of Wuhan University Third Peoples Hospital of Jingzhou City，430000 　　Abstract Objective：To evaluate the experience of the diagnosis and surgical treatment for patients with Primary Hyperparathyroidism.Methods：Retrospective study was done in 15 primary hyperparathyroidism cases who were treated surgically in our hospital between 2006 to 2013.The study included the clinical manifestations，biochemical analysis，pre and intraoperative radiological aid along with scintigraphy and surgical technique.Results：Among the 15 cases， the diagnose was accuracy with preoperative USG，CT and scintigraphy to localize the site of pathologic changes and.Following the operation，all of the patients had an uneventful recovery and the clinical symptoms were relieved gradually.The biochemical analysis returned to normal.There was no complication like long term hypoparathyroidism or damaged RLN in any of the cases.Conclusions：Clinical manifestation and adjuvant diagnostic tools are required for diagnostic accuracy of Hyperparathyroidism.Parathyroidectomy is an effective approach to patients with Primary Hyperparathyroidism.Preoperative and intraoperative localization of diseased site is an important factor that leads to favorable outcome. 　　Key words Primary Hyperparathyroidism；Parathyroid neoplasms；Surgical operation 　　原发性甲状旁腺功能亢进症（PHPT）是一种在我国比较少见的内分泌疾病，而在欧美国家多见，据报道，其每年的就诊率可达十万分之八[1]。笔者总结了本院2006-2013年收治的15例原发性甲状旁腺功能亢进症的临床和病理资料，报告如下。 　　资料与方法 　　2006-2013年收治并行手术治疗的PHPT患者15例，男6例，女9例，男女比1∶1.5，年龄14